Search results for "Complex systems biology"
showing 3 items of 3 documents
Mollusc shellomes: Past, present and future.
2020
13 pages; International audience; In molluscs, the shell fabrication requires a large array of secreted macromolecules including proteins and polysaccharides. Some of them are occluded in the shell during mineralization process and constitute the shell repertoire. The protein moieties, also called shell proteomes or, more simply, 'shellomes', are nowadays analyzed via high-throughput approaches. These latter, applied so far on about thirty genera, have evidenced the huge diversity of shellomes from model to model. They also pinpoint the recurrent presence of functional domains of diverse natures. Shell proteins are not only involved in guiding the mineral deposition, but also in enzymatic a…
General Systems Theory and Systems Biology
2015
We should not imagine that Systems Biology was born yesterday, indeed von Bertalanffy was a well-known supporter of the need to approach biological entities from the notion of a system. There is a tradition, dating back to early times, calling for the study of living things as a whole. Holism is no stranger to modern Systems Biology and, likewise, von Bertalanffy supported the quantitative study of the whole from the interaction of its parts.
On the modeling of nonlinear interactions in large complex systems
2010
Abstract This work deals with the modeling of large systems of interacting entities in the framework of the mathematical kinetic theory for active particles. The contents are specifically focused on the modeling of nonlinear interactions which is one of the most important issues in the mathematical approach to modeling and simulating complex systems, and which includes a learning–hiding dynamics. Applications are focused on the modeling of complex biological systems and on immune competition.